In a large heavy bottomed stock pot over medium high heat, cook the ground beef until browned, about 5-7 minutes, stirring occasionally. Drain the rendered fat and add the meat back to the pot.
Add the chopped onion, celery and garlic and cook until the vegetables soften, about 5-7 more minutes.
Add the rest of the ingredients (except the spaghtti noodles and Parmesan), stir, and bring to a boil. Reduce the heat to simmer, stir and cover with a lid, and cook for at least three hours on medium low heat, stirring occasionally.
Cook the spaghetti according to the package directions in generously salted water. Drain and mix into the spaghetti sauce.
Serve with grated or ground Parmesan cheese and chopped fresh parsley if desired.
The meat sauce can be refrigerated for up to 1 week or saved in a gallon ziplock bag and frozen for up to 3 months.